Limited Market Penetration and Adoption: The number of patients eligible and willing to undergo Inspire therapy remains a key constraint, and broadening market acceptance among patients and referring physicians, as well as increasing the number of trained implanting physicians, is critical for continued growth.

Intensifying Competition: While Inspire currently dominates the hypoglossal nerve stimulation market, new competitors developing similar or alternative medical devices, drug therapies, or surgical procedures for sleep apnea could emerge and capture market share.

Reimbursement Policy Changes: Inspire's revenue heavily relies on favorable reimbursement policies from government and private payers; any adverse changes in coverage, coding, or payment rates could significantly impact its financial performance.