Project Development and Construction Risks: Development of the Rook I project and other future mines involves significant technical, operational, and financial challenges, which could lead to construction delays, cost overruns, or failure to complete the project as planned, impacting future production and profitability.

Uranium Price Volatility: The profitability of Nexgen Energy is highly dependent on the global market price of uranium, which can be volatile due to factors like geopolitical events, nuclear power demand, supply disruptions, and inventory levels, potentially reducing revenue and project viability.

Regulatory and Permitting Complexities: Obtaining and maintaining the necessary permits, licenses, and approvals for uranium exploration, development, and mining operations from various governmental and Indigenous authorities is a complex and often lengthy process, subject to changes in laws and policies, which could cause significant delays or even prevent project advancement.